Cell Culture Roller Bottle

Description

A cell culture roller bottle is a kind of disposable container which can meet the requirements of large-scale production of cells and tissues in both experimental and industrial production and is widely used in the culture of animal and plant cells, bacteria, viruses and so on. Placed on rollers, the flask can slowly rotate and bathe cells attached to the inner surface of the bottle. Rollers are available in a variety of capacities and styles.

Product Parameter

■ TC Treated

Production Technology

01 Material: polystyrene (PS), which meets USP VI medical grade.

02 Injection, pull and blow molding process, the product bottle mouth is smooth and round, the contact sealing with the cap is better, and the product residue is less.

03 cGMP standard production, sterile, no endotoxin, no heat source, no cytotoxicity, and perfect quality system from the source to ensure product quality and consistency.

Features of Cell Culture Roller Bottle:

Fudau cell culture roller bottles are made of high-quality materials that ensure optimal cell growth and viability. The bottles are available in different sizes and configurations to meet the needs of various applications. 

Material: Fudau cell culture roller bottles are made of polystyrene (PS), which is a clear, rigid plastic that is biologically inert and resistant to many chemicals. PS is also compatible with most cell culture media, making it an ideal material for cell culture.

Surface Treatment: The inner surface of the Fudau cell culture roller bottle is treated with a special coating that promotes cell adhesion and growth. This coating also prevents cell detachment and clumping, which can compromise the quality of the culture.

Design: The Fudau cell culture roller bottle has a unique design that ensures optimal cell growth and oxygen exchange. The bottle has a straight, cylindrical shape with a large surface area, which provides ample space for cell attachment and proliferation. The bottle also has a convex bottom that promotes the even distribution of cells and media.

Advantages

Large Capacity: Fudau cell culture roller bottles are available in various sizes, ranging from 850ml to 1750ml, making them ideal for large-scale cell culture.

Efficient Nutrient Exchange: The rolling motion of the Fudau cell culture roller bottle ensures efficient nutrient exchange and oxygenation, leading to enhanced cell growth and viability.

Uniform Cell Growth: The design of the Fudau cell culture roller bottle promotes uniform cell growth and prevents cell clumping, ensuring high-quality cell cultures.

Sterility: Fudau cell culture roller bottles are sterilized using gamma radiation, ensuring a sterile environment for cell culture.

Our roller bottle cell culture products have a distinctive design that enhances cell growth and simplifies the harvesting process. They are ideal for various applications, such as cell expansion, virus production, and monoclonal antibody production. We offer roller bottle cell culture products in various sizes and configurations to cater to all applications. Therefore, we have the perfect roller bottle cell culture product for any of your needs.

Application

Vaccine production: Large-scale growth of virus-infected cells for vaccine production is a common use of roller bottles. The agitation of cells on the rollers with a serum-containing medium helps to increase the yield of viral particles.

Antibody production: Monoclonal and polyclonal antibodies are produced using roller bottles. The cells that produce the antibody are grown in the bottles, and the culture supernatant is harvested to obtain the antibodies.

Recombinant protein production: Roller bottles are utilized to produce recombinant proteins, including enzymes and growth factors. The protein is harvested from the culture supernatant or by lysing the cells after the cells producing the protein are grown in the roller bottles.

Cell line establishment: Roller bottles are commonly used for adherent cell line establishment. The cells are grown in the bottles until they reach confluency and then passaged to new bottles or other culture vessels.

Toxicity testing: Roller bottles can also be used for toxicity testing of chemicals or drugs. The cells are grown in the bottles and exposed to the compound of interest, and the viability and growth of the cells are monitored over time.