Spherical Bioreactor Carrier

Description

A spherical bioreactor carrier refers to a microcarrier that has a spherical shape and is utilized in various biotechnological applications. It is created by bonding diethylamino chloroethane onto agarose microspheres, which facilitates the attachment of cells to the carrier surface. Due to its effectiveness, it has become the most commonly employed microcarrier for adherent cell suspension culture.

This type of carrier plays a crucial role in the research, development, and production of biological products. It provides a favorable environment for the cultivation of cells and facilitates their growth and proliferation. The spherical shape of the carrier allows for efficient mixing and uniform distribution of nutrients and gases throughout the culture medium.

By using a spherical bioreactor carrier, researchers and biotechnologists can enhance the productivity and yield of their cell cultures. The cells easily attach to the carrier, promoting cell-cell interactions and the formation of three-dimensional structures, which can mimic the natural tissue environment more accurately. This characteristic is particularly valuable in tissue engineering and regenerative medicine applications.

The spherical bioreactor carrier is scalable, enabling the generation of large quantities of cells or biological products. The spherical bioreactor carrier is designed to offer several advantages over traditional flake bioreactor carriers. This makes it a preferred choice in pharmaceutical research and development, where the production of therapeutic proteins, vaccines, and other biological molecules is essential.

Parameter

Features

» Efficient and simple isolation of cultures and cells, harvesting of products, perfusion or continuous feeding.

» It can be cultured in large-scale stirred bioreactors,single-use bioreactors and shake flasks to provide sufficient surface area for cell growth.

» High area/volume ratio, high cell density.

» It is easy to enlarge the cells. The cells can be digested from the carrier and then inoculated into the new carrier, or the new carrier can be directly added to realize the "baU-to-ball" method to expand the culture.