Bromo-tris-pyrrolidino-phosphonium hexafluorophosphate （Pybrop ）cas 132705-51-2

Product Name: Bromo-tris-pyrrolidino-phosphonium hexafluorophosphate

Synonyms: pybrop;pybrop(r);pybrop(tm);bromotripyrrolidinophosphonium hexafluorophosphate;bromo-tris-pyrrolidino-phosphonium hexafluorophosphate;bromo-tris-pyrrolidino-phosphonium hexfluorophosphate;pybrop(bromo-tris-pyrrolidinophosphoniumhexafluorophosphate);pybrop\(rg

CAS: 132705-51-2

MF: C12H24BrF6N3P2

MW: 466.19

EINECS: 620-834-4  

Mol File: 132705-51-2.mol

The specification of Pybrop cas 132705-51-2

Usage of Pybrop cas 132705-51-2

It can be used as a coupling reagent:

•For Suzuki–Miyaura cross-coupling of phenols and arylboronic acids to synthesize biaryls and heterobiaryls.

•To functionalize pyrimidines (synthesized from 3,4-dihydropyrimidin-2(1H)-ones (DHPMs) via the Kappe dehydrogenation) by using various nucleophiles.

•To synthesize formamidines by coupling with various primary amines and N,N-diisopropylethylamine.

It can also be used as an activating reagent:

•For the activation of C-OH bond in tautomerizable heterocycles to form the phosphonium salt which aids the Sonogashira coupling of heterocycles with various alkynes.

•For the one–pot activation of C-O bond in phenols and further coupling reaction with phosphine oxide or phosphite to form C-P bonds.

Shandong Minglang Chemical Co., Ltd