Eprinomectin - USP

Eprinomectin is an abamectin used as a veterinary topical endectocide. It is a mixture of two chemical compounds, eprinomectin B1a and B1b. Eprinomectin is a highly effective, broad-spectrum, and low-residue veterinary anthelmintic drug that is the only broad-spectrum anthelmintic drug applied to lactating dairy cows without the need for milk abandonment and without the need for a rest period.

Eprinomectin is semi-synthesized from fermented abamectin B1. There are multiple components, but the two components B1a and B1b play the main role, and the impurities are not easy to control. The purity of the active ingredients of a drug determines the efficacy of the drug and is also the main cause of side effects. Jiayi Eprinomectin has high purity, strong activity and small side effects.

Short Description:

Eprinomectin Chemical Name: 4"-Table-Acetamido-4"-Deoxy Abamectin,

B1a: molecular formula C50H77NO14/molecular weight 916, B1b: molecular formula C40H75NO14/molecular weight 902

API family: eprinomectin

manufacturer/tradename: USP

Content: H2B1a+H2B1≥95.0% (calculated based on anhydrous and solvent) H2B1a/H2B1a+H2B1b≥90.0%.

Properties: This product is white or light yellow crystalline powder. Store in shading, dry and sealed at 2-8°C for 3 years

Eprinomectin is only approved for use in cattle and sheep abroad, and there is no withdrawal period when it is applied to dairy cows and beef cattle. Medication safety.

Eprinomectin CAS#: 123997-26-2, the quality standard meets the latest version of USP/enterprise, the packaging specification is 25kg/barrel, or customized by customers.

Principle of Medicine

The results of kinetic studies showed that acetylaminoavermectin can be absorbed by a variety of routes, such as oral or percutaneous, subcutaneous, and intramuscular injection, with good efficacy and rapid distribution throughout the body. However, to date, there are only two commercial preparations of acetylaminoavermectin: pouring agent and injection. Among them, the application of pouring agent in virulent animals is more convenient; while although the bioavailability of injection is high, the injection site pain is obvious and the disturbance to animals is greater. It has been found that oral absorption is superior to transdermal absorption for the control of nematodes and arthropods that feed on blood or body fluids.

Physicochemical properties

The drug substance is a white crystalline solid at room temperature, with a melting point of 173 ° C and a density of 1.23 g/cm3. Because of its lipophilic group in its molecular structure, its lipid solubility is high, it is soluble in organic solvents such as methanol, ethanol, propylene glycol, ethyl acetate, etc., has the greatest solubility in propylene glycol (greater than 400 g/L), and is almost insoluble in water. Eprinomectin is easy to photolyze and oxidize, and the drug substance should be protected from light and stored under vacuum.

Using

Eprinomectin has a good control effect in the control of internal and ectoparasites such as nematodes, hookworms, ascaris, helminths, insects and mites in various animals such as cattle, sheep, camels, and rabbits. It is mainly used for the treatment of gastrointestinal nematodes, itching mites and sarcoptic mange in livestock.

USP Eprinomectin - China Manufacturers, Suppliers, Factory

Looking for 123997-26-2 / Eprinomectin API manufacturers, exporters & distributors? Jiayi has DMF and is a large GMP-certified veterinary drug factory. We provide APIs, more than 100 own-label preparations, and OEM & ODM services. Jiayi established a complete quality management system and has a professional team of registration, sales and technical service, our company has gained reliance and support from numerous customers through excellent product quality, high-quality pre-sales and after-sales service, and serious and scientific management.